Peptide Hormones as Tumor Markers in Neuroendocrine Gastrointestinal Tumors
نویسندگان
چکیده
منابع مشابه
Circulating tumor cells as prognostic markers in neuroendocrine tumors.
PURPOSE To determine the prognostic significance of circulating tumor cells (CTCs) in patients with neuroendocrine cancer. PATIENTS AND METHODS In this single-center prospective study, 176 patients with measurable metastatic neuroendocrine tumors (NETs) were recruited. CTCs were measured using a semiautomated technique based on immunomagnetic separation of epithelial cell adhesion molecule-ex...
متن کاملGastrointestinal Neuroendocrine Tumors
Neuroendocrine tumors of the gastrointestinal tract are relatively rare neoplasms derived from the diffuse endocrine system (DES), and classified as APUDomas. These neoplasms include mainly pancreatic endocrine tumors (islet cells) and carcinoids. Although malignant, these tumors are often slow-growing. Frequently, these neoplasms secrete hormonal peptides and vasoactive amines that can produce...
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Gastrointestinal carcinoid tumors date back to 1888 when Otto Lubarsch found multiple tumors in the distal ileum of two patients at autopsy (Lubarsch, 1888). The German pathologist Siegfried Oberndorfer was the first who used the term “Karzinoide Tumoren”, the English translation of which is “carcinoid tumor”. He coined this term because these tumors behaved less aggressively than true carcinom...
متن کاملGastrointestinal neuroendocrine tumors.
Gastrointestinal neuroendocrine tumors (GI-NETs) are a genetically diverse group of malignancies that sometimes produce peptides causing characteristic hormonal syndromes. NETs can be clinically symptomatic (functioning) or silent (non-functioning); both types frequently synthesize more than one peptide, although often these are not associated with specific syndromes. Based on data from various...
متن کاملGastrointestinal Neuroendocrine Tumors in Two Children.
BACKGROUND Enterochromaffin-like cell hyperplasia and neuroendocrine tumors are relatively rare in childhood. CASE CHARACTERISTICS A 15-year-old girl who presented with epigastric pain and a 6-year-old boy who was admitted with hematochezia. Endoscopy revealed nodules in the stomach in Case 1, and polyploidy lesion in the rectum in Case 2. OUTCOME Enterochromaffin-like cell hyperplasia in C...
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ژورنال
عنوان ژورنال: Acta Oncologica
سال: 1991
ISSN: 0284-186X,1651-226X
DOI: 10.3109/02841869109092404